Which marker is associated with activated T Cells?

Get ready for the ASCP Specialist in Cytometry Test. Prepare with flashcards and multiple choice questions. Each question comes with hints and explanations to improve your knowledge. Ensure success in your exam!

The marker CD25 is associated with activated T cells, particularly those that have been stimulated and are undergoing proliferation. CD25 is the alpha subunit of the interleukin-2 (IL-2) receptor and its expression is upregulated during T cell activation. Activated T cells, which respond to immune challenges, increase the expression of CD25 to enhance their ability to respond to IL-2, a critical growth factor that promotes T cell proliferation and survival.

In contrast, other markers mentioned in the question serve different functions: CD20 is primarily a B cell marker involved in the regulation of B cell activation and is not typically associated with T cells. CD2 is a marker that is present on T cells but does not specifically indicate activation; rather, it is involved in cell adhesion and is expressed on all T cells. CD34 is a marker associated with hematopoietic stem cells and endothelial cells, and is not related to T cell activation. Therefore, the distinct association of CD25 with activated T cells sets it apart as the correct answer in this context.

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