What type of cells does the CD16 marker identify?

The CD16 marker is identified primarily on the surface of Natural Killer (NK) cells and monocytes. CD16, also known as FcγRIII, is a receptor for the Fc portion of immunoglobulin G (IgG) antibodies and plays a crucial role in the immune response. In the context of NK cells, CD16 is important for their ability to mediate antibody-dependent cellular cytotoxicity (ADCC), where NK cells can recognize and kill target cells coated with antibodies. Monocytes express CD16 at varying levels, and its presence can help distinguish subsets of monocytes, particularly those involved in inflammatory responses.

Understanding the specific markers associated with different cell types is essential for the identification and study of immune cell populations in both research and clinical settings. The distinct role of CD16 in mediating immune responses underscores its importance in identifying these two cell types effectively.